Before you start any attempt of diagnostics, you must choose a note to play with on the keyboard, and keep using always the same one.
You can eventually use different notes (keys) on the keyboard, but at least eight times each, and do not try to compare (yet) the G3 key and C3 key sounds, if you compare, it will be each same notes on the keyboard. Got it ?
First : what should be the original sound ? Just to compare the degradation.
An idiot came once and grabbed my head with a sound problem, and after an hour, he told me that big crack in the middle of the sample was normal, intended ! I tought I would kill him... So, now, I rather ask !
Use a pure and sustained sound, like flute or organ, not car crash samples
Second : is it a sound coming from a diskette
or did you sample it ?
Third : played
still on the same note, is the sound the same, with the degradation, or does it change randomly every time you press the key, (you must play this note at least eight times, in order to scan all the channels).
If, on the same note, the sound is the same, disable all channels except channel one and try. Is the degratadtion there ?
After then, disable channel one, enable channel two, and on the same note, is the sound the same ?
Same thing, till channel eight.
Let us know...